The Hong Research Group is located in the Department of Biopharmaceutical Sciences at University of Illinois at Chicago. The newly-renovated first-class laboratory is located within the UIC college of pharmacy that is in the heart of the Illinois Medical District, which includes the University of Illinois Medical Center, Rush University Hospitals, and other health science colleges and hospitals.
WHAT WE DO?
Our research focus lies at the interface of materials science, biology and nanotechnology to develop novel polymeric nanodevices for biological analysis, diagnostics and therapeutics. The ultimate goal of our laboratory is to achieve marriage of biomimetics and nanotechnology. Our work is being conducted in a highly interdisciplinary and collaborative environment that provides opportunities for students with backgrounds and/or interests in chemistry, engineering, biology, medicine and pharmaceutical sciences.
More specifically, we are interested in understanding and controlling biological interactions of polymers with cells at the nano-scale. The fundamental understanding will lead us to more translational cancer research fields including: i) Targeted drug delivery with enhanced targeting efficacy using newly designed nanocarriers; ii) Local, transdermal delivery of drugs such as chemo-preventive medicine; and iii) Biomimetic multifunctional devices for effective detection and isolation of rare cells such as circulating tumor cells (CTCs).
From left to right, Seungpyo Hong, Ashley Cha, Jason Bugno, Suhair Sunoqrot, Ryan Pearson, Yang Yang, Kevin Tam, Jeeho Lee, Hao-jui Hsu, Frehiwot Gebrehiwot, Matthew Pasco, Ja Hye Myung
Missing members: Marilyn Gaske
Our paper entitlted "Eradication of acute myeloid leukemia with FLT3 ligand-targeted miR-150 nanoparticles" is published by Cancer Research. This is our 2nd paper coming out of the collaboratioin with Dr. Chen group. Members of our group, Jason (co-first author), Yang, and Dr. Hong (co-corresponding author), co-authored this exciting paper!
Our paper entitlted "Tuninig the Selectivity of Dendron Micelles through Variations for the Poly(ethylene glycol) Corona" is accepted for publication by ACS Nano! The authors are Ryan, Soumyo, Hao-jui, Matt, Marilyn, Dr. Kral, and Dr. Hong.
Jason receives 2016 AAPS Graduate Fellowship that is given to only 4 Pharmaceutical Science students in the US. Congratulations!
Our collaborative paper entitlted "miR-22 has a potent anti-tumour role with therapeutic potential in acute myeloid leukaemia" is on-line published by Nature Communications! This paper reports our collaboration with Dr. Jianjun Chen's group at U of Cincinnati (formerly at U of Chicago). Among many authors of our collaborators at U of Chicago and U of Cincinnati, members of our group, including Jason, Yang, and Dr. Hong, are listed as co-authors.
Our recent article published in WIREs Nanomedicine & Nanobiotechnology is selected for the cover image! The paper is entitled "Recent Advances in Nanotechnology-based Detection and Separation of Circulating Tumor Cells" co-authored by Ja Hye, Kevin, Sin-jung, Ashley, and Dr. Hong.
Our review paper entitled "Dendrimer-based nanocarriers: a versatile platform for drug delivery" is accepted for publication by WIREs Nanomedicine & Nanobiotechnology. The authors are Hao-jui, Jason, Seung-ri, and Dr. Hong. Congratulations!
The US News and World Report releases the newest ranking that puts our College at #6 among all US Colleges of Pharmacy.
Our paper with our collaborators (Dr. J. Chen's group at U of Cincinatti) entitled "miR-22 Plays a Potent Anit-Tumor Role with Therapeutic Potential in Acute Myeloid Leukemia” is accepted for publication in Nature Communications! Jason, Yang, and Dr. Hong are among the co-authors!
Dr. Hong is appointed as Associate Editor for journal Nanomedicine: Nanotechnology, Biology and Medicine published by Elsevier. The journal has 2014 ISI impact factor of 6.155 and 5-year impact factor of 7.275!
Dr. Hong gives a keynote speech at the Annual Research Festival of Department of Organic and Nano Engineering, Hanyang University, Seoul, KOREA.
Dr. Hong gives an invited talk at the Korea Society of Pharmaceutical Science and Technology (KSPST) Annual Meeting held in Sungnam, KOREA.
Dr. Hong joins IEEE-Nanomed meeting held in Honolulu, HI where he serves on the organizing commitee, chairs a session and delivers an invited talk.